Several studies have confirmed that Omega-3 supplements are far better absorbed when taken with a high fat meal.
This applies to both Omega-3 capsules and liquid. Fatty fish such as Salmon already has other fats present which help drive absorption in the body.
It is hypothesized that the configuration of fatty acids in whole fish is familiar to our body and thus easier to absorb.
Omega-3s have many benefits in the body and to maximise these take your Omega-3 supplements once per day (for simplicity) with your meal that contains the most amount of fat.